In this episode, Dr. Marsh explains the neuroscience of altruism, from the role of the amygdala to genetic influences on empathy. Through Dr. Marsh’s donor stories and research insights we explore the spectrum of altruism and psychopathy. She reveals how the amygdala, the brain region tied to emotional responses, plays a pivotal role in altruistic behavior. Remarkably, research shows that altruistic kidney donors often have larger amygdala sizes compared to the average person.

Dr. Marsh also reveals the genetic factors that shape empathy and altruistic tendencies, while challenging the misconception that altruism is irrational or abnormal. She contrasts the media’s frequent focus on negative aspects of human nature with the lived experiences of donors, who describe profound feelings of honor and fulfillment after giving the gift of life.

Throughout the conversation, personal stories from living organ donors underscore the importance of community support for both donors and recipients. Dr. Marsh emphasizes the power of education and awareness to dispel myths about donation and highlights that altruism is not only a natural human trait but also one that can be nurtured and encouraged in all of us.

Links and Resources

Dr. Marsh’s Website

Dr. Marsh’s TedTalk

The Fear Factor, by Dr. Marsh

Dr. Marsh LinkedIn

Connect with the Podcast or Learn more about Organ Donation

Click here for more information about living organ donation.

Click here for more information about living kidney transplantation. 

Click here for more information about Polycystic Kidney Disease. 

Ajmera Transplant Centre on Instagram

Each episode, we share patient stories about organ donation from transplant recipients and living donors, along with insights and education from leading medical experts. Whether you’re a patient, a caregiver, a donor, or simply curious about the world of organ transplantation, you’ll hear expert advice and inspiring journeys of hope, resilience, and second chances.

About our Host

Candice Coghlan is the Education & Outreach Coordinator at the Centre for Living Organ Donation at the UHN Ajmera Transplant Centre. She is also a board member for the National Kidney Foundation and a kidney transplant recipient. After she was diagnosed with kidney failure in her early 20s, she was on dialysis until receiving a transplant from her mother.

Have questions? Comments? Ideas for an episode? Please reach out to the Centre for Living Organ Donation at livingorgandonation@uhn.ca. Thanks for spending your time with us.

The views and opinions expressed in this episode do not necessarily reflect the official policy or position of Toronto General or University Health Network.